Main title

|||

About

The purpose of the Institutional Biosafety and Bioethics Committee (IBEC) is to ensure safe and ethical research at KAUST involving: human subjects; animals via IACUC review; biological materials; biologically derived toxins; genetically modified organisms; plants, especially invasive species or noxious weeds; potentially infectious environmental samples and corresponding cultures; human-derived materials (e.g., blood, tissues, embryonic stem cells, primary cell lines, etc.); recombinant or synthetic nucleic acids; viral vectors; gene-editing techniques such as CRISPR/Cas9; nanotechnology and other developing biologically relevant technologies; and researcher that poses a potential risk to living organisms and the environment.

  • Animals - via notification from the Institutional Animal Care and Use Committee (IACUC) of approved animal study proposals and through periodic reports from IACUC
  • Biological materials, including biohazardous agents (Risk Group 2; Risk Group 1 agents must be registered with the Biosafety Officer; they are not reviewed by IBEC unless increased risk is identified); biologically derived toxins; genetically modified organisms; plants, especially invasive species or noxious weeds; potentially infectious environmental samples and corresponding cultures; human-derived materials (e.g., blood, tissues, embryonic stem cells, primary cell lines, etc.); recombinant or synthetic nucleic acids; and viral vectors
  • Gene-editing techniques such as CRISPR/Cas9
  • Human subjects
  • Nanotechnology and other developing, biologically relevant technologies
  • Potential risk to living organisms and the environment

National Registration/Accreditation

Saudi Arabia’s National Committee of Bioethics (NCBE) registration

KAUST’s Institutional Biosafety and Bioethics Committee (IBEC) serves as the registered local committee for all National Committee of Bioethics (NCBE)-regulated activities.

IBEC Responsibilities
Approval, Evaluation and Review
  • Approve standard procedures and forms regarding biosafety and bioethics for investigators to use
  • Approve and review modifications to approved research activities
  • Evaluate the experience of the Principal Investigator and their team to conduct the research with regard to biosafety and bioethics
  • Evaluate biological containment plans to ensure that adequate containment measures exist
  • Review research proposals at intervals appropriate to the degree of risk and as required by the National Committee of Bioethics (NCBE) standards; the approval period shall not exceed 3 year
  • Review all incidents and accidents regarding biosafety and bioethics
  • Review the effectiveness of the University’s bioethics program and provide recommendations to the Research Operations and Compliance and VPR
  • Review the effectiveness of the Biosafety Manual and provide recommendations to Health, Safety and Environment (HSE)
Training

  • Establish training procedures and criteria regarding biosafety and bioethics
  • Ensure that the Principal Investigator and the research team have completed all committee-required training

Non-Compliance

  • Investigate alleged non-compliance of biosafety and bioethics
  • Suspend non-compliant research with regard to biosafety and bioethics or with regard to unexpected harm to research subjects
  • Provide a written statement outlining the reasons for suspension of non-compliant research addressed to the Principal Investigator, respective Dean, and Research Operations and Compliance